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Medicine that inhibit CYP2D6 action, such as paroxetine and quinidine, may possibly bring about diminished clearance of oxycodone which may lead to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Check with your health practitioner or pharma